CorneaMD

CorneaMD: A Multiomics Database for Corneal Diseases

GSE197745

Publication

Comparative single-cell transcriptomic analysis across tissues of aging primates reveals specific autologous activation of ZNF281 to mitigate oxidative stress in cornea

Species

Macaca fascicularis

Source

Corneal epithelium

Condition

Aging

Technology

scRNA-seq

Cell number

14912

Abbreviations

LSC, Limbal stem cell; PMC, Postmitotic cell; Conj‐1, Conjunctival epithelial cells‐1; TDC, Terminally differentiated cell; Conj‐2, Conjunctival epithelial cells‐2; TAC, Transit amplifying cell; MC, Melanocyte

Groups

Ctrl (corneal epithelium of diabetic crab-eating monkey, n=1); DM (corneal epithelium of healthy crab-eating monkey, n=1).

Citation

Xiao, Yuhua et al. "Comparative single-cell transcriptomic analysis across tissues of aging primates reveals specific autologous activation of ZNF281 to mitigate oxidative stress in cornea." Aging cell vol. 23,12 (2024): e14319. doi:10.1111/acel.14319

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