CorneaMD

Welcome to CorneaMD
CorneaMD is an integrated multi-omics database for corneal diseases, consolidating transcriptomic, single-cell, epigenomic, proteomic and metabolomic data to empower systematic investigations. Designed for intuitive exploration, we provides powerful search functionalities and analytical tools to investigate disease-gene relationships and multi-omics interactions. By bridging the gap between complex molecular data and clinical insights, this database serves as an indispensable resource for uncovering novel mechanisms, biomarkers, and therapeutic targets in corneal disease research.

Portal
Transcriptomics Bulk RNA-seq \| DEG analysis \| Visualization \| Functional enrichment						Single-cell UMAP/tSNE \| Cell proportion \| Markers \| Functional enrichment \| Signature score
Spatial-map Chip \| UMAP/tSNE \| Cell proportion \| Markers \| Functional enrichment \| Signature score						Epigenomics ChIP-seq \| scATAC-seq \| DAR analysis \| Functional enrichment \| IGV
Proteomics LFQ/TMT \| DDA/DIA \| DEP analysis \| Visualization \| Functional enrichment						Metabolomics DAM analysis \| Visualization \| Functional enrichment

Data visualization

Gene expression

Cell type statistics

Differential expression

Signature score

Protein PCA

DAMs heatmap

Functional enrichment

scATAC-seq

ChIP-seq

Spatial-map

Genes & Diseases

Database information

Corneal diseases/Conditions	64
Tissues	28
Datasets	143
Data types	18
Cell types	176
Cell number	1,302,881
Protein-coding genes	88,711
Non-coding RNA	178,971
Variants	114
Studies	97

Global visitors

News & data releases

2025.10.1 The epigenomics data was online.

2025.10.1 Document update and refinement.

2025.9.1 The IGV plugin was available.

2025.8.1 The metabolomics data was online.

2025.7.1 The gene-disease search module was online.

2025.5.1 Clinical Images collection for gene-disease search module.

2025.4.1 Variants collection for the gene-disease search module.

2025.2.1 Data collection and processing for microarray data.

2025.1.1 The RNA array data was online.

2024.11.1 The proteomics data was available.

2024.10.1 Data collection and processing for proteomics data.

2024.7.1 Data collection for the gene-disease search module.

2024.6.1 The single-cell module was available online.

2023.11.1 The bulk RNA-seq data was launched.

2023.9.1 Data collection for transcriptomics and single-cell data.

2023.6.1 The dedicated domain name was approved.

2023.4.1 The database framework was completed.

Welcome to CorneaMD
CorneaMD is an integrated multi-omics database for corneal diseases, consolidating transcriptomic, single-cell, epigenomic, proteomic and metabolomic data to empower systematic investigations. Designed for intuitive exploration, we provides powerful search functionalities and analytical tools to investigate disease-gene relationships and multi-omics interactions. By bridging the gap between complex molecular data and clinical insights, this database serves as an indispensable resource for uncovering novel mechanisms, biomarkers, and therapeutic targets in corneal disease research.

Portal
Transcriptomics Bulk RNA-seq \| DEG analysis \| Visualization \| Functional enrichment						Single-cell UMAP/tSNE \| Cell proportion \| Markers \| Functional enrichment \| Signature score
Spatial-map Chip \| UMAP/tSNE \| Cell proportion \| Markers \| Functional enrichment \| Signature score						Epigenomics ChIP-seq \| scATAC-seq \| DAR analysis \| Functional enrichment \| IGV
Proteomics LFQ/TMT \| DDA/DIA \| DEP analysis \| Visualization \| Functional enrichment						Metabolomics DAM analysis \| Visualization \| Functional enrichment