Single-cell transcriptomics reveals the molecular basis of human iPS cell differentiation into ectodermal ocular lineages

Human

hiPSC-derived SEAM

Organoid

scRNA-seq

4671

RPE, Retinal pigment epithelium; RPCs/NR, Retinal progenitor cells/neural retina cells; Proliferating RPCs, Proliferating retinal progenitor cells; Corneal epi, Corneal epithelium; RGCs, Retinal ganglion cells; migCorneal epi, Migratory corneal epithelium; Non-ocular epi, Non-ocular epithelium; MG, Müller glia sells; PRs, Photoreceptors; Lacrimal gland, Lacrimal gland cells.

Patrick-Brown, Thale D J Hovdun et al. "The effects of remdesivir on long-term symptoms in patients hospitalised for COVID-19: a pre-specified exploratory analysis." Communications medicine vol. 4,1 (2024): 231. doi:10.1038/s43856-024-00650-4

WK10_2024_Commun_Biol_hiPSCs-SEAM.rds

60