Single-cell transcriptomics reveals the molecular basis of human iPS cell differentiation into ectodermal ocular lineages

Human

hiPSC-derived SEAM

Organoid

scRNA-seq

4125

RPE, Retinal pigment epithelium; RPCs/NR, Retinal progenitor cells/neural retina cells; Proliferating RPCs, Proliferating retinal progenitor cells; Corneal epi, Corneal epithelium; RGCs, Retinal ganglion cells; Mucosal epi, Mucosal epithelium; iMG, Immature müller glia; PRs, Photoreceptors; Endothelial, Endothelial cells.

Lengler, Johannes et al. "Crucial aspects for maintaining rAAV stability." Scientific reports vol. 14,1 (2024): 27685. doi:10.1038/s41598-024-79369-0

WK8_2024_Commun_Biol_hiPSCs-SEAM.rds

59