Publication
A single cell atlas of human cornea that defines its development, limbal progenitor cells and their interactions with the immune cells
Species
Human
Source
Whole cornea
Condition
Keratoconus
Technology
scRNA-seq
Cell number
23984
Abbreviations
BV, Blood vessels; CB, Corneal basal epithelium; CS, Corneal superficial epithelium; CSB, Corneal suprabasal epithelial cells; CjB, Conjunctival basal epithelium; CjS, Conjunctival superficial epithelium; CE, Corneal endothelium; CSK, Corneal stroma keratocytes; CSSCs, Corneal stromal stem cells; FCEC, Fibroblastic corneal endothelial cells; IC1, Immune cells 1; LF, Limbal fibroblasts; LSB, Limbal suprabasal epithelial cells; LSK, Limbal stroma keratocytes; LNCPs, Limbal neural crest progenitors; LPCs, Limbal progenitor cells; LS, Limbal superficial epithelium; LV, Lymphatic vessels; MEL, Melanocytes; RBC, Red blood cells.
Groups
Ctrl (normal central cornea, n=1); KC (keratoconus cornea, n=2).
Citation
Collin, Joseph et al. "A single cell atlas of human cornea that defines its development, limbal progenitor cells and their interactions with the immune cells." The ocular surface vol. 21 (2021): 21. doi:10.1016/j.jtos.2021.03.010
Group_GSE155683_keratoconus.rds
32