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CorneaMD: A Multiomics Database for Corneal Diseases

  HRA000728
  Publication
Single-cell atlas of keratoconus corneas revealed aberrant transcriptional signatures and implicated mechanical stretch as a trigger for keratoconus pathogenesis
  Species
Human
  Source
Central cornea
  Condition
Keratoconus
  Technology
scRNA-seq
  Cell number
39214
  Abbreviations
CSC, Corneal stroma cell; CEC, Corneal epithelium cell; ImC, Immune cell.
  Groups
Ctrl (normal central cornea, n=4); KC (keratoconus central cornea, n=3).
  Citation
Dou, Shengqian et al. "Single-cell atlas of keratoconus corneas revealed aberrant transcriptional signatures and implicated mechanical stretch as a trigger for keratoconus pathogenesis." Cell discovery vol. 8,1 66. 12 Jul. 2022. doi:10.1038/s41421-022-00397-z

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